Scientists have discovered new epigenetic factors in cancer development.
The researchers presented findings based on a large-scale study of epigenetic changes that occur in cancer cells.
The research sheds light on the ability of cancer cells to adapt to adverse conditions, Cancer Discovery reports.
Experts believe that cancer cells undergo epigenetic modifications that help them successfully adapt and survive in an unfavorable environment.
Scientists believe that excessive DNA methylation suppresses genes responsible for the body's protective functions against tumors.
The study showed the activation of ancient viral sequences in the human genome.
In addition, scientists have discovered a disruption in the process of modifying histone proteins in cancer cells.
These changes affect the structure of the cell nucleus and lead to epigenetic instability.
As a result, favorable conditions are created for the development of malignant neoplasms.
Scientists emphasize that genetic and epigenetic changes enhance each other's influence.
The results of the study will improve methods of diagnosing and treating oncology.